ABSTRACT
Background: The localized inflammatory reaction to periodontal pathogenic bacteria or bacterial products is characterized by penetration of the periodontal tissues by inflammatory cells. Recent studies demonstrate the relation between periodontal disease (PD) and hyperlipidemia, which influence the likelihood of PD as an underlying factor for hyperlipidemia. Aim: The aim of this Randomized, case-control type of study was to elucidate the association between serum lipid parameters in periodontally diseased patients with healthy individuals. Material and methods: A total number of 44 subjects were segregated into two groups Group A (Control) Group B (Test). Periodontal parameters including Oral hygiene Index-Simplified (OHI-S), Gingival Index (GI), Probing Depth (PD) and Clinical Attachment Level (CAL) were recorded. Lipid profile comprising of Serum cholesterol, Triglycerides, HDL- Cholesterol and LDL was assessed and co related with periodontal parameters. Vani Chappidi, Pradeep Koppolu, Lingam Amara Swapna, Sridhar Reddy Erugula, Krishnajaneya Reddy Pathakota. Effect of Chronic Periodontitis on Serum Lipid Profile: A Randomized, Case Control Clinico-biochemical Study. IAIM, 2017; 4(10): 67-71. Page 68 Results: The results of the present study demonstrated a positive correlation between GI, PD, OHI-S and CAL with serum cholesterol, TG and LDL. The Serum cholesterol, Triglycerides and LDL levels between both the groups showed statistical significance. But the serum HDL levels when compared between both the groups were not statistically significant. Conclusion: The present study showed a definitive positive correlation between PD and increased lipid levels.
ABSTRACT
The diagnosis of vesiculo-bullous lesions and many other diseases is fundamentally based on the microscopic study of cells and tissues. This diagnostic method remains the standard, by which all other diagnostic tests are measured. Nevertheless, the era of the pathologist relying entirely on the examination of tissue sections stained by histochemical methods is gradually being replaced by a time Sridhar Reddy Erugula, P. Sujatha, Jesudass Govada, B. Suresh Reddy, B. Kavitha Reddy, Oruganti Venkata Ramanand, Pothuraju Haritha, Kandukuri Mahesh Kumar. Histopathological features and immunoflorescence patterns in skin lesions. IAIM, 2016; 3(11): 171-183. Page 172 when advanced immunologic and molecular techniques (i.e. analysis of DNA, RNA or protein structure and function) augment the process by which complicated diseases are classified.
ABSTRACT
Vesiculobullous lesions are a type of mucocutaneous disease that is characterized by vesicles and bullae or blisters. Both vesicles and bullae are fluid-filled lesions, and they are distinguished by size, vesicles being less than 5–10 mm and bulla being larger than 5–10 mm, In the case of vesiculobullous diseases which are also immune disorders the term immunobullous is sometimes used. This review will provide an overview of vesiculobullous lesions involving oral cavity, their characteristic features and recent developments in the diagnosis of these lesions.